Diabetes has long been known to increase the risk of heart attack or stroke at an early age. But not only that to worry about. Diabetes also significantly increases the risk of Alzheimer's disease or severe memory loss later in life.
A study published in the journal Neurology reveal the relationship. Researchers found that people with diabetes are two times greater risk of suffering from Alzheimer's disease within 15 years.
Diabetics also 1.75 times more at risk of developing dementia or dementia. The study was conducted on more than 1,000 men and women over the age of 60 years.
The researchers argue, diabetes contributed to dementia (dementia) in several ways. Insulin resistance causes high blood sugar and trigger type 2 diabetes can interfere with the body's ability to break down protein that forms brain plaques associated with Alzheimer's.
High blood sugar (glucose) also produces certain oxygen-containing molecules that can damage cells or also known as the process of oxidative stress.
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addition, high blood sugar and cholesterol in diabetics causing hardening and narrowing of blood vessels in the brain. A condition known as atherosclerosis can cause vascular dementia, which is dementia that occurs due to clogging of the arteries (including strokes) kill brain tissue.
"Glucose levels were high trigger pressure on the nervous system and blood vessels. Some of the information related to Alzheimer's disease and glucose levels have shown us that we need to remain alert to blood sugar levels as we get older," says David Geldmacher, MD, professor of neurology at the University of Alabama at Birmingham as reported by CNN,
The study, led by Yutaka Kiyohara, MD, medical researchers neighborhood of Kyushu University in Fukuoka is a gold standard diagnosis of diabetes, the oral glucose tolerance test.
The trick is to give someone a drink of sugar after fasting for at least 12 hours. Levels of glucose in their blood and then measured two hours later.
At the beginning of the study, tests showed that 15% of the participants had diabetes, while 23% had prediabetes condition also known as impaired glucose tolerance.
The participants did not have dementia at all when the test was done. But 15 years later, 23% of participants received a diagnosis of dementia. Only half of dementia cases are regarded as Alzheimer's disease.
While the rest is a combination of vascular dementia and dementia due to other causes. Diagnosis is confirmed by brain scans of patients who are still alive and brain autopsies on patients who had died.
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