Overlapping DNA, Persons with Autism Precisely Small Risk of Esophageal Cancer

Overlapping DNA, Persons with Autism Precisely Small Risk of Esophageal Cancer

Behind every trial, usually always stored extraordinary wisdom. This condition might describe the results of recent research on autism.
Although until now the cause of autism is not known clearly, but most experts believe autism is triggered by a change in genetic factors. But who would have thought this would have a positive impact change for the experience.
From the results of observations conducted by Dr. Benjamin Darbro (University of Iowa), persons with autism had a smaller risk of developing cancer, although genetic mutations that they experienced more than those who were not autistic.
Darbro get this fact after comparing the DNA database DNA autism patients with those who are not autistic. As expected, the autistic patients have a gene variation that is more diverse, and mostly related to conditions such as epilepsy and intellectual decline.
But the researchers also found an oncogene diversity in their DNA. Oncogene is a gene that plays a role in the early stages of tumor formation and the presence of this gene, the chances of normal cells into tumor cells or cancer in a person's body becomes larger.
That means, when viewed genetically, autism patients has great potential for cancer. But once the data is matched with the patient's medical record autism and compared with those who are not autistic, rarely found their cancer diagnosis in those with autism.
From the comparison between 1837 and 9336 autism patients with other diagnoses patients found that 3.9 is not autistic patients had cancer. While those who have symptoms of autism at the same risk of cancer is only 1.3 percent. That is, the autistic 66 percent lower risk of cancer diagnosed.
"There is the possibility of cancer-promoting genes with each other autismenya spill-overlapping so that it provides a protective effect," said Darbro reported Science Daily.
Even stronger protective effect was seen in younger patients. The younger the patient, the effect of the stronger protection. So for autistic patients aged 14 years and below, the opportunity to receive a diagnosis of cancer was reduced by 94 percent.
Darbro hope the findings could have implications for the development of new anti-cancer drugs, and vice versa explore other potential cancer drugs for treating the symptoms of autism.

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