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A study showed that exposure to bacteria early in life is very important for children to not prone to autoimmune disease throughout his life.
These findings support the hypothesis that the bacteria needed to build a healthy immune system. Lifestyle fear and avoid bacteria actually increase the risk of asthma, allergies and other autoimmune diseases.
The immune system is the frontline in defense against germs around the body. Nasty germs that can cause food poisoning, colds and other diseases. However, most of these germs were not dangerous and some are even healthful.
To combat infection, immune cells or white blood cells are programmed to look for a foreign protein from a cell that is not from the body. Unfortunately, the white blood cells sometimes assume the parts of the body's own cells as foreign and attack them. These disturbances are called autoimmune diseases. Allergies, asthma and blood cancer is a form of
autoimmune disease.
In a study published in the journal Science, the researchers compared normal mice with mice raised in a germ-free special. Researchers then measured the levels of white blood cells called invariant natural killer T cells (iNKT) in the lungs and the intestines of mice.
INKT cells release proteins that cause inflammation. Inflammation plays an important role in autoimmune diseases. INKT cells are known to be active in the lungs in asthma sufferers and patients with stomach ulcerative colitis or inflammation of the colon.
"Between the two mice, the most striking difference is the susceptibility to autoimmune diseases. Mice that were free of germs is much more susceptible to disease than mice that have been exposed to the bacteria," said the researcher, Dennis Lee Kasper, senior physician at Brigham and Women's Hospital in Boston as LiveScience reported .
When exposed to the bacteria at a later date, even germ-free mice still had iNKT cells are abundant in the lungs and intestines. This suggests that the formation of the immune system in the early period of life is very important in the formation of proper immune system.
"Exposure to the bacteria in infancy is important to protect the body from inflammation and cell INKT. Not only for the diseases mentioned above, it could be such exposure also may protect children from type 1 diabetes," said Axel Kornerup Hansen, a professor at the University of Copenhagen Denmark is not involved in the research.
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